| Alfred Historic District | Alfred | District | 1983 |
| Alfred Shaker Historic District | Alfred | District | 2001 |
| Austin-Hennessey Homestead | Wells | Building | 1979 |
| Ayer, Caleb R., House | Cornish | Building | 2002 |
| Badger, Samuel, Monument | Kittery Foreside | Object | 1998 |
| Barrell Homestead | York Corner | Building | 1976 |
| Berwick Academy | South Berwick | District | 1978 |
| Berwick Academy Historic District (Boundary Increase) | South Berwick | District | 1996 |
| Berwick High School | Berwick | Building | 2012 |
| Biddeford City Hall | Biddeford | Building | 1973 |
| Biddeford Main Street Historic District | Biddeford | District | 2009 |
| Biddeford-Saco Mills Historic District (Additional Documentation) | Biddeford | District | 2008 |
| Biddeford-Saco Mills Historic District (Boundary Increase) | Biddeford | District | 2022 |
| Blazo-Leavitt House | Parsonsfield | Building | 1982 |
| Boon Island Light Station | York | District | 1988 |
| Bourne Mansion | Kennebunk | Building | 1980 |
| Brave Boat Harbor Farm | York | District | 2007 |
| Bray House | Kittery Point | Building | 1979 |
| Breckinridge, Isabella, House | York | Building | 1983 |
| Brewster, Royal, House | Buxton | Building | 1975 |
| Buxton Powder House | Buxton Center | Building | 1976 |
| Cape Arundel Golf Club | Kennebunkport | District | 2009 |
| Cape Arundel Summer Colony Historic District | Kennebunkport | District | 1984 |
| Cape Neddick Light Station | York | Building | 1985 |
| Chase, Capt. Josiah E., Octagon House | East Limington | Building | 1987 |
| Clifford, George F., House | Cornish | Building | 2010 |
| Clock Farm | Kennebunkport | Building | 1982 |
| Colonial Inn | Ogunquit | District | 2012 |
| Conant-Sawyer Cottage | York Beach | Building | 1992 |
| Conway Junction Railroad Turntable Site | South Berwick | Site | 1989 |
| Cummings Shoe Factory | South Berwick | Building | 2001 |
| Cummings' Guest House | Old Orchard Beach | Building | 2004 |
| Dalton, Benjamin and Abigail, House | North Parsonsfield | Building | 1997 |
| Deering, J. G., House | Saco | Building | 1982 |
| Dennett Garrison | Kittery | Building | 1978 |
| District No. 5 School | Alfred | Building | 2009 |
| Division No. 9 School | North Berwick | Building | 1995 |
| Dorfield Farm | Wells | Building | 1979 |
| Dudley Block | Biddeford | Building | 1982 |
| Early Post Office | Wells | Building | 1979 |
| Eaton House | North Berwick | Building | 1979 |
| Elden's Store | Buxton | Building | 1983 |
| Elder Grey Meetinghouse | North Waterboro | Building | 1979 |
| Emery Homestead | Sanford | Building | 1980 |
| Emery House | Highpine | Building | 1979 |
| Emery School | Biddeford | Building | 2011 |
| First Baptist Church | Waterboro | Building | 1988 |
| First Congregational Church and Parsonage | Kittery Point | Building | 1978 |
| First Congregational Church and Parsonage (Boundary Increase) | Kittery Point | District | 1997 |
| First Congregational Church of Buxton | Buxton | Building | 1980 |
| First Congregational Church, Former | Wells | Building | 1991 |
| First Parish Meetinghouse | Biddeford | Building | 1972 |
| Flagg, James Montgomery, House | Biddeford | Building | 1980 |
| Fletcher's Neck Lifesaving Station | Biddeford Pool | Building | 1974 |
| Fogg, William, Library | Eliot | Building | 1991 |
| Fort McClary | Kittery Point | Building | 1969 |
| Foss, Levi, House | Goodwins Mills | Building | 1984 |
| Frisbee, Frank C., Elementary School | Kittery | Building | 2012 |
| Frost Garrison and House | Eliot | District | 1971 |
| Goat Island Light Station | Cape Porpoise | District | 1988 |
| Goodale-Bourne Farm | Ogunquit | Building | 1979 |
| Goodale-Stevens Farm | Ogunquit | Building | 1979 |
| Goodall Worsted Company Alpaca Mill No. 2 - Jagger Brothers Mill | Sanford | Building | 2025 |
| Goodall, Louis B., Memorial Library | Sanford | Building | 2008 |
| Goodall, Thomas, House | Sanford | Building | 1975 |
| Goodwin, Edmund E., House | Sanford | Building | 2015 |
| Grant Family House | Saco | Building | 1990 |
| Graves, Abbott, House | Kennebunkport | Building | 1980 |
| Grist Mill Bridge | Lebanon | Structure | 1990 |
| Hamilton, Jonathan, House NHL | South Berwick | Building | 1970 |
| Hancock, John, Warehouse | York | Building | 1969 |
| Harper Family House | Limerick | Building | 1998 |
| Hatch House | North Berwick | Building | 1979 |
| Hawkes Pharmacy | York Beach | Building | 1993 |
| Hedden Site | Kennebunk | Site | 1991 |
| Historical and Architectural Resources of Eliot, Maine MPS | Eliot | | |
| Hobbs, Thomas, Jr., House | North Berwick | Building | 1982 |
| Holmes, Sen. John, House | Alfred | Building | 1975 |
| Howels, William Dean, House | Kittery Point | Building | 1979 |
| Hurd, Mary R., House | North Berwick | Building | 1979 |
| Hussey Plow Company Building | North Berwick | Building | 1979 |
| Isles of Shoals | Kittery | District | 1974 |
| Jacobs Houses and Store | Saco | Building | 1982 |
| Jewett, Sarah Orne, House NHL | South Berwick | Building | 1973 |
| Jewett-Eastman House | South Berwick | Building | 1983 |
| Johnson, Dennis, Lumber Company Mill | Waterboro | Building | 2007 |
| Jones, John Paul, Memorial Park | Kittery Foreside | District | 1998 |
| Kennebunk High School | Kennebunk | Building | 2011 |
| Kennebunk Historic District (Additional Documentation) | Kennebunk | District | 1974 |
| Kennebunk River Club | Kennebunkport | Building | 1975 |
| Kennebunkport Historic District | Kennebunkport | District | 1976 |
| Kezar Falls Circulating Library | Parsonsfield | Building | 2021 |
| Lady Pepperrell House NHL | Kittery Point | Building | 1966 |
| Laudholm Farm | Wells | Building | 1983 |
| Laudholm Farm (Boundary Increase) | Wells | District | 1987 |
| Leavitt, James, House | Waterboro Center | Building | 2004 |
| Libby's Colonial Tea Room | Wells | Building | 2001 |
| Libby-MacArthur House | Limington | Building | 1988 |
| Limerick Upper Village Historic District | Limerick | District | 1984 |
| Limington Academy | Limington | Building | 1980 |
| Limington Historic District | Limington | District | 1999 |
| Lincoln School | Acton | Building | 2013 |
| Littlefield Homestead | Wells | Building | 1979 |
| Littlefield Tavern | North Berwick | Building | 1979 |
| Littlefield-Chase Farmstead | North Berwick | Building | 1979 |
| Littlefield-Dustin Farm | North Berwick | Building | 1979 |
| Littlefield-Keeping House | North Berwick | Building | 1979 |
| Lord Farm | Wells | Building | 1979 |
| Lord Mansion | Kennebunk | Building | 1973 |
| Lord, Capt. Nathaniel, Mansion | Kennebunkport | Building | 1973 |
| Lord-Dane House | Alfred | Building | 1992 |
| Lower Alewive Historic District | Kennebunk | District | 1994 |
| Maine Trolley Cars | Kennebunkport | Structure | 1980 |
| Marginal Way | Ogunquit | Structure | 2022 |
| McIntire Garrison House NHL | York | Building | 1968 |
| Memorial Chapel | Berwick | Building | 2018 |
| Mill House | Ogunquit | Building | 1979 |
| Moody Homestead | York | Building | 1975 |
| Morison, Capt. James, House | Parsonsfield | Building | 1978 |
| Morrell House | North Berwick | Building | 1976 |
| Newfield (Willowbrook) Historic District | Newfield | District | 1985 |
| North Berwick Woolen Mill | North Berwick | Building | 1983 |
| Ocean Park Historic Buildings | Ocean Park | Building | 1982 |
| Odd Fellows-Rebekah Hall | Cornish | Building | 1983 |
| Ogunquit Memorial Library | Ogunquit | Building | 1983 |
| Ogunquit Playhouse | Ogunquit | Building | 1995 |
| Old Grist Mill | East Lebanon | Building | 1975 |
| Old Schoolhouse | York | Building | 1973 |
| Old Town House | Parsonsfield | Building | 2002 |
| Old York Gaol NHL | York | Building | 1968 |
| Parsons-Piper-Lord-Roy Farm | Parsonsfield | Building | 2005 |
| Parsonsfield Seminary | Parsonsfield | Building | 1986 |
| Paul Family Farm | Eliot | District | 1998 |
| Pebbledene | York Beach | Building | 1993 |
| Pepperrell, William, House | Kittery Point | Building | 1973 |
| Perkins, Charles, House | Ogunquit | Building | 1979 |
| Pike, LeRoy F., Memorial Building | Cornish | Building | 2007 |
| Portsmouth Company Cotton Mills: Counting House | South Berwick | Building | 1975 |
| Portsmouth Naval Shipyard | Kittery | District | 1977 |
| Prescott, J. L., House | North Berwick | Building | 1985 |
| Rendezvous Point Burying Ground | Saco | Site | 2021 |
| Rice Public Library | Kittery | Building | 1979 |
| Rock Rest | Kittery | Building | 2008 |
| Rose, Robert, Tavern | York | Building | 1975 |
| Saco Central Fire Station | Saco | Building | 2013 |
| Saco City Hall | Saco | Building | 1979 |
| Saco High School (old) | Saco | Building | 1983 |
| Saco Historic District | Saco | District | 1998 |
| Salmon Falls (East) Historic District | Buxton | District | 1987 |
| Salmon Falls (West) Historic District | Hollis | District | 1987 |
| Sanford Mills Historic District | Sanford | District | 2009 |
| Sanford Town Hall (Former) | Springvale | Building | 2007 |
| Seavey, A. B., House | Saco | Building | 1978 |
| Sedgley, John, Homestead | York Corner | Building | 1976 |
| Smith, James, Homestead | Kennebunk | Building | 1982 |
| Smith-Emery House | Springvale | Building | 1998 |
| South Berwick Village Historic District | South Berwick | District | 2010 |
| Spiller Farm Paleoindian Site | Wells | Site | 2003 |
| St. Andre's Parish | Biddeford | District | 2015 |
| St. Joseph's School | Biddeford | Building | 1983 |
| St. Peter's By-The-Sea Protestant Episcopal Church | Cape Neddick | Building | 1999 |
| Stage Island Monument | Biddeford | Structure | 2019 |
| Staples Inn | Old Orchard Beach | Building | 1987 |
| Summer Street Block | Biddeford | Building | 2024 |
| Sunnycroft | Limerick | Building | 1984 |
| Tarr, John, House | Biddeford | Building | 1980 |
| Temple, The | Old Orchard Beach | Building | 1975 |
| Thacher-Goodale House | Saco | Building | 1976 |
| Timber Point | Biddeford | District | 2016 |
| Traip, Robert and Louisa, House | Kittery Foreside | Building | 1998 |
| U.S. Customhouse | Kennebunkport | Building | 1974 |
| U.S. Post Office | Biddeford | Building | 1973 |
| US Post Office-Sanford Main | Sanford | Building | 1986 |
| Vines, Richard, Monument | Biddeford | Object | 2022 |
| Wallingford Hall | Kennebunk | Building | 2004 |
| Waterboro Grange, No. 432 | Waterboro | Building | 2012 |
| Way Way General Store | Saco | Building | 1995 |
| Welch, Andrew, Homestead | Parsonsfield | Building | 2002 |
| Wells Baptist Church Parsonage | Wells | Building | 1979 |
| Wells Homestead | Wells | Building | 1979 |
| Wentworth, Mark F. and Eliza J., House | Kittery Foreside | Building | 1998 |
| West Lebanon Historic District | West Lebanon | District | 1975 |
| Whaleback Light Station | Kittery Point | Structure | 1988 |
| Wiggin, Kate Douglas, House | Hollis Center | Building | 1977 |
| Winn House | Ogunquit | Building | 1979 |
| Wood Island Light Station | Biddeford Pool | District | 1988 |
| York Cliffs Historic District | York | District | 1984 |
| York Historic District | York | District | 1973 |