| Acorn Woman Peak Lookout (Additional Documentation) | Jacksonville | Building | 2000 |
| Ahlstrom, Nils, House | Ashland | Building | 1980 |
| Anderson, Thomas N., House | Gold Hill | Building | 1990 |
| Antelope Creek Covered Bridge | Eagle Point | Site | 2012 |
| Ashland Cemetery | Ashland | Site | 1995 |
| Ashland Depot Hotel, South Wing | Ashland | Building | 1991 |
| Ashland Downtown Historic District | Ashland | District | 2000 |
| Ashland Masonic Lodge Building | Ashland | Building | 1992 |
| Ashland Municipal Powerhouse | Ashland | Building | 1987 |
| Ashland Oregon National Guard Armory | Ashland | Building | 1987 |
| Ashland Railroad Addition Historic District | Ashland | District | 1999 |
| Atkinson, W. H., House | Ashland | Building | 1979 |
| BPOE Lodge No. 1168 | Medford | Building | 1980 |
| Baker, Sophenia Ish, House | Medford | Building | 1993 |
| Barclay-Klum House | Ashland | Building | 1990 |
| Barnum Hotel | Medford | Building | 1984 |
| Beach, Baldwin, House | Ashland | Building | 1979 |
| Beall, Robert Vinton, House | Central Point | Building | 1979 |
| Beeson-Foss Ranch | Talent | Building | 1999 |
| Big Elk Guard Station | Ashland | Building | 2000 |
| Boslough-Claycomb House | Ashland | Building | 1981 |
| Bowne, Walter, House | Jacksonville | Building | 1990 |
| Britt Gardens Site 35JA789 | Jacksonville | Site | 2020 |
| Buckhorn Mineral Springs Resort | Ashland | District | 1989 |
| Bursell, Victor and Bertha, House | Central Point | Building | 1982 |
| Butte Falls Ranger Station | Butte Falls | Building | 1986 |
| Bybee, Frank E., House | Jacksonville | Building | 1981 |
| Bybee, William, House | Medford | Building | 1977 |
| Camp White Station Hospital Administration Building | White City | Building | 2016 |
| Campbell, Richard Posey, House | Ashland | Building | 1980 |
| Carpenter, A.S.V., and Helen Bundy House | Central Point | Building | 2005 |
| Carter, E. V., House | Ashland | Building | 1979 |
| Carter, H. B., House | Ashland | Building | 1977 |
| Carter-Fortmiller House | Ashland | Building | 1981 |
| Central Point Public School | Central Point | Building | 1980 |
| Chappell-Swedenburg House | Ashland | Building | 1982 |
| Chavner Family House | Gold Hill | Building | 1996 |
| Citizen's Banking & Trust Co. Building | Ashland | Building | 1985 |
| Clark, Frank Chamberlain, House | Medford | Building | 1982 |
| Cooley-Neff Warehouse | Medford | Building | 2007 |
| Coolidge, Orlando, House | Ashland | Building | 1980 |
| Corning Court Ensemble | Medford | Building | 1991 |
| Dead Indian Soda Springs Shelter | Eagle Point | Structure | 2000 |
| Driver, E. Raymond, House | Central Point | Building | 1990 |
| Dunn, Patrick, Ranch | Ashland | Building | 1978 |
| Dutchman Peak Lookout | Ashland | Building | 2000 |
| Eagle Point National Cemetery | Eagle Point | District | 2016 |
| Eddings-Provost House | Ashland | Building | 1980 |
| Eden Valley Orchard | Medford | Building | 2000 |
| Egan, H. Chandler and Alice B., House | Medford | Building | 1997 |
| Enders Building | Ashland | Building | 1986 |
| Faber, Edward Charles, House | Central Point | Building | 1997 |
| First Baptist Church | Ashland | Building | 1979 |
| First National Bank, Vaupel Store and Oregon Hotel Buildings | Ashland | Building | 1980 |
| Fish Lake Shelter | Ashland | Structure | 2000 |
| Fluhrer Bakery Building | Medford | Building | 1983 |
| Fort Lane Military Post Site | Central Point | Site | 1988 |
| Fredenburg, Andrew J., House | Medford | Building | 1982 |
| Furry, Frederic E., House | Medford | Building | 1980 |
| Gates, C. E. "Pop", House | Medford | Building | 1991 |
| Glenview Orchard Ensemble | Phoenix | Building | 1986 |
| Gold Hill High School | Gold Hill | Building | 1991 |
| Grainger, G. M. and Kate, House | Ashland | Building | 1990 |
| Hafer, Edgar F., House | Medford | Building | 1983 |
| Hanley, Michael, Farmstead | Medford | District | 1983 |
| Hanscom Hall | Talent | Building | 1996 |
| Hargadine Cemetery | Ashland | Site | 1998 |
| Hatch, Charles and Elizabeth, House | Rogue River | Building | 2011 |
| Hillcrest Orchard Historic District | Medford | District | 1984 |
| Holmes, Harry and Eleanor, House | Medford | Building | 2021 |
| Hover, George A., House | Medford | Building | 1980 |
| IOOF Building | Ashland | Building | 1978 |
| Imnaha Guard Station | Butte Falls | Building | 1986 |
| Jackson County Courthouse | Medford | Building | 1986 |
| Jacksonville Historic District NHL | Jacksonville | District | 1966 |
| Jacksonville-to-Fort Klamath Military Wagon Road | Butte Falls | Site | 1979 |
| Kane, E. C., House | Ashland | Building | 1986 |
| Lee-Janouch House | Medford | Building | 2025 |
| Liberty Building | Medford | Building | 1978 |
| Lithia Park | Ashland | District | 1982 |
| Lithia Springs Hotel | Ashland | Building | 1978 |
| Lodgepole Guard Station | Butte Falls | Building | 1991 |
| Lost Creek Bridge | Lakecreek | Structure | 1979 |
| Lucas, Robert and Ruth, House and Mary E. Rose House | Ashland | Building | 1988 |
| Madden-McCaskey House | Central Point | Building | 1994 |
| Malmgren Garage | Talent | Building | 2024 |
| McCall, John, House | Ashland | Building | 1981 |
| McCredie, William, House | Central Point | Building | 1980 |
| McKee Bridge | Ruch | Structure | 1979 |
| McKee Bridge Campground | Jacksonville | Site | 2000 |
| McManus, Patrick F., House | Phoenix | Building | 1978 |
| Medford Carnegie Library | Medford | Building | 1981 |
| Medford Central Firehall | Medford | Building | 1996 |
| Medford Downtown Historic District | Medford | District | 1998 |
| Medford Geneva-Minnesota Historic District | Medford | Building | 1994 |
| Medford Grocery Company Warehouse | Medford | Building | 2002 |
| Medford IOOF Cemetery | Medford | District | 1989 |
| Medford Plaza Apartments | Medford | Building | 2004 |
| Medford Southern Pacific Railroad Passenger Depot | Medford | Building | 1996 |
| Merritt, John W., House and Store | Central Point | Building | 1992 |
| Mountain House | Ashland | Building | 2004 |
| Mountain View Cemetery | Ashland | Site | 1995 |
| Mt. Stella Lookout | Prospect | Building | 2000 |
| Nininger, Amos and Vera, House | Ashland | Building | 1982 |
| Orth, John, House | Jacksonville | Building | 1972 |
| Parker Meadows Shelter | Butte Falls | Structure | 2000 |
| Parsons, Reginald, Dead Indian Lodge | Ashland | Building | 1997 |
| Patton, Hamilton and Edith, House | Medford | Building | 1993 |
| Pedigrift, S. and Sarah J., House | Ashland | Building | 1992 |
| Peerless Rooms Building | Ashland | Building | 1992 |
| Peil, Emil and Alice Applegate, House | Ashland | Building | 1992 |
| Pelton, John and Charlotte, House | Ashland | Building | 1993 |
| Perozzi, Domingo, House | Ashland | Building | 1980 |
| Pickel, Dr. E. B., Rental House | Medford | Building | 1982 |
| Pracht, Humboldt, House | Ashland | Building | 1981 |
| Prospect Hotel | Prospect | Building | 1980 |
| Putnam-Neff House | Medford | Building | 2008 |
| Reames, Alfred Evan, House | Medford | Building | 1991 |
| Reddy, Dr. John F. and Mary, House | Medford | Building | 1987 |
| Rich Gulch Diggings | Jacksonville | Site | 2000 |
| Rock Point Hotel | Gold Hill | Building | 1980 |
| Rogue Elk Hotel | Trail | Building | 1980 |
| Root-Banks House | Medford | Building | 1994 |
| Roper, Fordyce, House-Southern Oregon Hospital | Ashland | Building | 1985 |
| Schuler Apartment Building | Medford | Building | 1991 |
| Shone-Charley House | Medford | Building | 1984 |
| Silsby, Col. William H., House | Ashland | Building | 1985 |
| Siskiyou-Hargandine Historic District | Ashland | District | 2002 |
| Skidmore Academy Historic District | Ashland | District | 2001 |
| Snowy Butte Flour Mill | Eagle Point | Building | 1976 |
| South Oakdale Historic District | Medford | District | 1979 |
| Sparta Building | Medford | Building | 1992 |
| Star Ranger Station | Ruch | Building | 1991 |
| Star Ranger Station Building, Old | Jacksonville | Building | 2000 |
| Sweeney, Dr. Charles T. and Mary, House | Medford | Building | 1992 |
| Talent Elementary School | Talent | Building | 2012 |
| Taverner, George, House | Ashland | Building | 1978 |
| Tayler-Phipps Building | Medford | Building | 1990 |
| Trinity Episcopal Church | Ashland | Building | 1984 |
| U.S. Post Office and Courthouse | Medford | Building | 1979 |
| Union Creek Historic District | Prospect | District | 1980 |
| Van Hoevenberg, Henry, Jr., House | Gold Hill | Building | 1981 |
| Wagner Creek School | Talent | Building | 1992 |
| Walker, John P., House | Ashland | Building | 1978 |
| Washington Elementary School | Medford | Building | 2012 |
| Welch, Mathias, House | Central Point | Building | 1998 |
| West Side Feed and Sale Stable | Medford | Building | 1981 |
| Whaleback Snow-Survey Cabin | Prospect | Building | 2000 |
| White John B., House | Rock Point | Building | 1978 |
| Whited, Harry L., House | Ashland | Building | 1998 |
| Whittle Garage Building | Ashland | Building | 1997 |
| Wilkinson-Swem Building | Medford | Building | 1982 |
| Willow Prairie Cabin | Butte Falls | Building | 2000 |
| Women's Civic Improvement Clubhouse | Ashland | Building | 1989 |
| Woolen, Isaac, House | Ashland | Building | 1979 |
| Wrangle Gap Shelter | Ashland | Structure | 2000 |